Franck Polleux, PhD
Dr. Franck Polleux did his undergraduate and graduate studies at UniversitÃ© Claude Bernard in Lyon, (France) where he obtained his Ph.D. in Neuroscience in 1997. He then joined the laboratory of Dr. Anirvan Ghosh at Johns Hopkins University for his post-doctoral training. In 2002, Dr Polleux was hired as an Assistant Professor in the Neuroscience Center and Department of Pharmacology at the University of North Carolina- Chapel Hill where he became an Associate Professor in 2008. In August 2010, he joined The Scripps Research Institute in La Jolla, California.
In November 2013, he was recruited as a Professor in the Department of Neuroscience at Columbia University to join the new Mortimer B. Zuckerman Mind, Brain, Behavior Institute.
Throughout his career, Dr Polleux has focused on the identification of the molecular mechanisms underlying neuronal development in the mammalian brain. More recently, his lab started studying the genetic basis of human brain evolution as well as the signaling pathways underlying synaptic loss during early stages of Alzheimer’s Disease progression.
- Professor of Neuroscience
Credentials & Experience
Honors & Awards
- 1993-1997 Graduate Training Award from the French Ministry of Research and Technology
- 1999 Albert L. Lehninger Research Prize for Post-doctoral Research - Johns Hopkins University
- 2000-2001 INSERM-CFB award for a European collaborative project with the group of Dr Vanderhaeghen, University of Brussels –Belgium.
- 2004-2007 March of Dimes Birth Defect Foundation Award
- 2005-2009 Pew Scholar Award in Biomedical Sciences
- 2005-2007 NARSAD Young Investigator Award
- 2007-2009 NARSAD Young Investigator Award
- 2008-2012 Permanent member on NIH Study Section Neuronal Differentiation, Plasticity and Regeneration (NDPR)
- 2010-2012 Co-Chair (2010) and Chair (2012) Gordon Conference, Neural Development - Salve Regina, RI
- 2012 Member of the Editorial Board of PLoS Biology
- 2015 Recipient of the 2015 Prize from the Fondation Roger de Spoelberch in Neuroscience (Scientific award for mid-career neuroscientists)
- Axon Pathfinding and Synaptogenesis
- Cell Specification and Differentiation
- Synapses and Circuits
Lewis, T.L.*, Kwon SK.*, Lee A., Shaw and Polleux F. (2018) MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size Nature Communications 9:5008.* Co-first authors.
Courchet V., Roberts, A.J., Del Carmine, P. Lewis TL. Polleux F. * Courchet J. * (2018) Happloinsufficiency of autism candidate gene NUAK1 impairs cortical development and behavior. Nature Communications9:4289. * co-corresponding authors
Hirabayashi Y., Tapia JC., Polleux F. (2018) Correlated Light-Serial Scanning Electron Microscopy (CoLSSEM) for ultrastructural visualization of single neurons in vivo. Scientific Reports 8:14491.